Hypochlorhydria refers to a condition where the stomach does not produce enough hydrochloric acid (HCl)

What is Hypochlorhydria?

Hypochlorhydria is the medical term for a deficiency in the production of gastric acid (stomach acid), specifically hydrochloric acid, in the digestive tract.

Who is affected?

Hypochlorhydria can affect individuals of any age group but is more common in older adults. Certain conditions and lifestyle factors can increase the risk, including chronic H. pylori infection, long-term use of proton pump inhibitors, gastric surgery, and autoimmune conditions.

When does hypochlorhydria occur or get diagnosed?

It may be diagnosed at any age. Symptoms that might lead to diagnosis include bloating, indigestion, deficiencies in nutrients, diarrhea, or discomfort after eating, especially when these symptoms persist or are severe. Typically, patients might undergo tests for stomach acidity if they present these symptoms.

Why does hypochlorhydria happen?

Causes can vary and include the following:


The stomach lining can thin and produce less acid.

Autoimmune condition

For example, pernicious anemia can affect the stomach's ability to produce acid.

Long-term use of antacids or other medication

Certain drugs like proton pump inhibitors used to treat acid reflux can lead to decreased acid production.

Chronic infection, like Helicobacter pylori, which can damage the stomach lining.

How is hypochlorhydria treated or managed?

Treatment depends on the cause. If medication is the cause, adjusting or changing the medication might be necessary. For nutrient deficiencies, supplements may be recommended. In some cases, betaine HCl supplements are used to increase stomach acid. Lifestyle and dietary changes are also common recommendations. Always under medical supervision.


Self-diagnosing and treating presumed hypochlorhydria with over-the-counter supplements or drastic diet changes without medical advice can be harmful. It's also important not to ignore the symptoms, as they might indicate other more serious conditions. Avoiding medical consultation and relying on unproven or anecdotal treatments might exacerbate the condition or neglect other underlying health issues.

While these are general insights, anyone suspecting they have hypochlorhydria or experiencing related symptoms should consult a healthcare professional for a proper diagnosis and treatment plan. Each individual's situation might require a unique approach depending on the underlying cause and overall health.